Any meaningful UX testing in 2023 needs to account for ad blockers and password managers.
If your site or app doesn’t work with popular ad blockers, or it refuses to allow logins pasted in from password managers, it’s broken.
Yes, some executive type will want to argue about this because they think ad blocking will go away or they misunderstood some now outdated infosec guidance. They’re wrong. Users use ad blockers and password managers and if your stuff doesn’t work with them, it’s broken.